Wednesday, May 7, 2014

- C - G- A- A- G- G- T- C- A- T- G- A - T - C - G- C - T- T- T- C- C- A- G-T- A- C- T- A- GDoes the deletion in the DNA molecule change the...

In the sequence above, if the DNA molecule has a deletion,
the UGA or stop codon, will occur in the mRNA complementary to the ACT triplet in the
DNA, just before the end of the DNA template, but, not at the end. This stop codon will
cause the ribosome to cease adding any further amino acids to the polypeptide chain. It
will cause the protein to be slightly shorter than normal. If this is the case, when the
protein detaches from the ribsome, and goes on to fold into a three dimensional shape,
it may not be functional or fully functional because it might have a distorted shape.
This can lead to a disorder or disease in a person when a necessary protein is not
functional.

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